Resident Evil: Extinction(2007)

Following the events of the Raccoon City incident in Apocalypse, the T-Virus escaped containment despite the nuclear destruction of the city. Now spreading through the ground, the Umbrella Corporation was unable to contain it. The virus spread across the country, drying up the lakes, rivers, and continents while infecting the majority of the population. After five years, almost every living creature has become a zombie, and the world itself is on the verge of extinction. The Umbrella Corporation appears to be the only organized society of humans left in the world, its remnants forced to live underground in Hive-like constructs dispersed around the world. Alice (Milla Jovovich), Umbrella's greatest Bio-Organic Weapon, is now alone in the desert wastelands of the remains of the United States after learning that the corporation has the ability to track her location via satellite. She has super-human strength and psionic abilities gained from her brief imprisonment by Umbrella. Umbrella considers re-capturing Alice a top priority because of her blood's ability to bond with the T-Virus. Dr. Sam Isaacs (Iain Glen) believes that he can develop a permanent cure to save what is left of humanity, as well as tame the zombies so as to create a viable workforce by using blood from the original Alice. Umbrella chief Albert Wesker (Jason O'Mara) orders Isaacs to create a cure without Alice, using clones created from her blood. Wesker refuses to authorize manpower to recover Alice until they are 100% sure where she is, due to the high risk involved in missions on the surface. The Alice clones endure tests within the re-created Spencer Mansion, The Hive, and Raccoon City Hospital locations, but none survive. The bodies of the failed Alices are dumped in a drainage ditch alongside Umbrella's fenced in desert compound, as hordes of zombies are gathered around the outside. Attempted cures derived from the cloned blood do not work, but Dr. Isaacs discovers that he can create a new strain of "super zombie" that can run, are unusually aggressive, and have even more strength. Isaacs secretly begins creating a horde of these new super zombies.